The TransCelerate BioPharma Digital Data Flow (DDF) workstream conducted a virtual Hackathon to evaluate feasibility for the Study Design component of the DDF Vision. The DDF Hackathon attracted 175 participants to provide innovative solutions to meet user needs described in 15 user stories with the goal to help transform our workflow from document-based to a content driven-data, design, workflow, and management environment. This webinar is a demonstration of the three Distinguished Submissions; each one a robust, impressive, and innovative prototype.